Table 2.
Results of the Elevated Plus-Maze Test and Locomotor Activity Test in Experiment 1A.
| Experiment 1A | Vehicle (n = 9) |
10 mg / kg WAY 267,464 (n = 6) |
100 mg / kg WAY 267,464 (n = 7) |
|---|---|---|---|
| Elevated plus-maze | |||
| Open arm time (%) | 16.6 ± 2.2 | 14.6 ± 2.4 | 13.7 ± 1.5 |
| Open arm entries (n) | 11.4 ± 1.1 | 7.8 ± 1.5 | 8.4 ± 1.2 |
| Total arm entries (n) | 17.2 ± 1.7 | 13.0 ± 2.4 | 13.1 ± 1.5 |
| Risk assessment (s) | 21.2 ± 2.2 | 35.2 ± 10.8 | 21.0 ± 1.9 |
| Locomotor activity test | |||
| Distance travelled (m) | 35.6 ± 5.2 | 29.2 ± 4.3 | 15.2 ± 1.7a,b |
a
Significantly different from vehicle;
b
Significantly different from 10 mg / kg WAY 267,464. Data are represented as the mean ± SEM.