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. Author manuscript; available in PMC: 2012 Jul 18.
Published in final edited form as: J Neuroendocrinol. 2012 Jul;24(7):1012–1029. doi: 10.1111/j.1365-2826.2012.02311.x

Table 4.

Mean ± SEM number of c-Fos Immunoreactive Cells in the Regions with Significant Differences between the Vehicle (n = 8), 1 mg / kg Oxytocin (n = 8) and 100 mg / kg WAY 267,464 (n = 8) Conditions.

Region (Fig. 1) Bregma Vehicle 1 mg/ kg
Oxytocin
100 mg / kg
WAY 267,464
Areas with significant WAY 267,464- and oxytocin-induced c-Fos
 expression above vehicle
  18. Paraventricular hypothalamic nucleus −1.80 8.7 ± 2.7 72.4 ± 13.5a 102.4 ± 17.2a
  20. Central amygdala −2.80 2.9 ± 0.7 25.5 ± 3.2a 20.6 ± 3.3a
  35. Lateral parabrachial nucleus −9.30 2.6 ± 1.3 18.0 ± 0.6a 13.1 ± 2.0a
  37. Nucleus of the solitary tract −13.68 1.5 ± 0.7 39.3 ± 5.3a 32.6 ± 6.2a
Areas with significant WAY 267,464-induced c-Fos expression above
 oxytocin and / or vehicle
  1. Medial prefrontal cortex / Prelimbic cortex +2.70 9.5 ± 2.0 3.9 ± 1.4 12.0 ± 2.8b
  12. Median preoptic nucleus −0.26 4.9 ± 1.0 8.4 ± 1.2 11.9 ± 2.2a
  16. Supraoptic nucleus (× 40) −1.30 4.6 ± 2.6 11.0 ± 4.0 41.5 ± 9.3a,b
  27. Medial amygdala (posterodorsal) −3.14 6.0 ± 1.5 6.0 ± 1.7 15.8 ± 1.7b
  34. Periaqueductal grey (ventrolateral) −8.72 3.4 ± 1.0 6.9 ± 1.4 9.4 ± 1.8a
Areas with significant oxytocin-induced c-Fos expression above WAY
 267,464 and / or vehicle
  36. Locus coeruleus −9.68 0.1 ± 0.1 5.9 ± 1.3a,c 1.6 ± 0.8
Areas with significant oxytocin-induced c-Fos expression below WAY
 267,464 and / or vehicle
  26. Lateral habenula −3.14 6.5 ± 1.8 1.1 ± 0.6a,c 6.3 ± 1.3
Areas with significant oxytocin-induced c-Fos expression above vehicle
  11. Bed nucleus of the stria terminalis (dorsolateral nucleus) (× 40) −0.26 3.1 ± 1.0 10.8 ± 2.4a 6.1 ± 1.1
a

Significantly different from vehicle;

b

Significantly different from oxytocin;

c

Significantly different from WAY 267,464. All counts were conducted at × 20 magnification, unless stated otherwise (× 40).