Table 2.

Comparison of the Thermodynamic Binding Parameters of GRFT and 1GS-S

		Affinity (μM)	ΔH (kcal/mol)	ΔG (kcal/mol)	TΔS (kcal/mol)
Mannosea	GRFT	102.0 ± 13.0	−0.081 ± 0.002	−5.53 ± 0.08	5.54 ± 0.08
1→2α- mannobiose	GRFT	53.9 ± 6.6	−0.173 ± 0.003	−5.91 ± 0.07	5.74 ± 0.07
	1GS-S	55.9 ± 14.3	−0.292 ± 0.012	−5.80 ± 0.21	5.50 ± 0.21
1→3α- mannobiose	GRFT	50.5 ± 8.3	−0.169 ± 0.005	−5.95 ± 0.10	5.76 ± 0.10
	1GS-S	46.1 ± 8.4	−0.310 ± 0.008	−5.91 ± 0.13	5.60 ± 0.13
1→6α- mannobiosea	GRFT	83.3 ± 17.5	−0.072 ± 0.002	−5.65 ± 0.12	5.58 ± 0.12
	1GS-S	84.7 ± 13.7	−0.202 ± 0.008	−5.55 ± 0.09	5.35 ± 0.09
Mannopentaose	GRFT	18.9 ± 2.8	−1.20 ± 0.14	−6.54 ± 0.88	5.35 ± 0.14
	1GS-S	15.1 ± 1.3	−1.83 ± 0.05	−6.57 ± 0.05	4.74 ± 0.05
Nonamannoside	GRFT	0.50 ± 0.16	−13.50 ± 0.11	−8.73 ± 0.31	−4.75 ± 0.31
	1GS-S	0.51 ± 0.22	−11.70 ± 1.73	−8.58 ± 0.56	−3.08 ± 1.10
gp120a	GRFT	0.008 ± 0.004	−30.40 ± 0.26	−11.20 ± 0.28	−19.16 ± 0.28
	1GS-S	0.112 ± 0.050	−35.50 ± 0.56	−9.47 ± 0.68	−25.99 ± 0.67

^aPreviously published (O'Keefe et al., 2010, Ziólkowska et al., 2007b, Ziólkowska et al., 2007a).