Table 4.
Anti-HIV Activity of GRFT Mutants
| Sample | EC50 (nM) | Form |
|---|---|---|
| GRFT | <0.2 | Dimer |
| S65W | <0.3 | Dimer |
| S65Y/S106E | <0.2 | Dimer |
| S65Y/E119I | 0.5 | Dimer |
| S65Y/K6V | 0.4 | Dimer |
| S65Y/L2V | 0.5 | Dimer |
| 1GS | 7 | Monomer |
| 2GS | 17 | Monomer |
| 1GS-S | 323 | Monomer |
| 1GS-SDNΔY | 305 | Monomer |
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