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. 2012 Jul 18;7(7):e41140. doi: 10.1371/journal.pone.0041140

Figure 2. Tumor growth delay after treatments.

Figure 2

Among the four treatment groups, ZdTha induced the longest delay in tumor growth over the examined period. (A) Representative axial images of liver tumors, acquired with T2-weighted images (T2WI) (TR/TE = 3860/106 ms). Top row: The tumors (arrows) in both left and right liver lobes showed very little growth over the examined period of ZdTha treatment. Row 2: The right tumor regrew rapidly from 2 d after Zd treatment; note the reduction in central necrosis (open arrow); Row 3: The tumor grew remarkably during Tha treatment; Bottom row: The tumor grew significantly in the control group. (B) Tumor volume changes after treatment compared to pretreatment measured on T2WI in the four treatment groups (mean ± standard deviation). Between 2 d and 12 d after treatment, the ZdTha group exhibited significantly smaller tumor volume changes compared to the other 3 groups (P<0.05) (Table S1).