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. 2012 Jul 18;7(7):e41382. doi: 10.1371/journal.pone.0041382

Figure 2. Effect of 2′OMe AONs targeting the initiator AUGs of FMDV RNA in in vitro translation efficiency.

Figure 2

(A). Autoradiograph of translation products obtained from in vitro synthetized FMDV RNA annealed, or not, with the indicated AONs and incubated with reticulocyte lysates. Translation assays were conducted as described in Material and Methods. The position of molecular weight markers is indicated on the left. (B). The intensity of the lanes were determined by densitometry and made relative to the total intensity of the lane without any AON, which was set at 100%. Data corresponds to the mean and standard deviation of the mean of three independent assays (*** P<0.01; ** P<0.05). A black bar denotes inhibitory capacity relative to the control translation reaction.