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. 2012 Jul 18;7(7):e41382. doi: 10.1371/journal.pone.0041382

Figure 7. Monitoring time-effect of virus yield induced by 2′OMe AONs complementary to the IRES region.

Figure 7

FMDV RNA was annealed with the indicated AONs and a scramble (SCR), prior to transfect confluent BHK-21 cell monolayers in duplicate. Virus yield was determined as PFU/ml in the supernatant 48 hpt, and made relative to the value obtained in the control RNA. Values represent the mean and standard deviation of triplicate assays. A black bar denotes inhibitory capacity (*** P<0.01) relative to control transfection.