Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Jul 18;7(7):e40787. doi: 10.1371/journal.pone.0040787

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Zamanian et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

Phylogenetic analysis was performed using planarian (S. mediterranea and D. japonica), parasite (S. mansoni), human and C. elegans 5-HT receptors and putative 5-HT receptors. TM domains I-VII were were extracted from the alignment for bootstrapping (bootstrap value 1000). Outlined receptors are significantly diverged from vertebrate and ecdysozoan serotonin receptors. DtSER-1 (red) was amplified using a degenerate PCR strategy and was chosen to undergo RNAi-based deorphanization.

Inline graphic — Phylogenetic analysis was performed using planarian (S. mediterranea and D. japonica), parasite (S. mansoni), human and C. elegans 5-HT receptors and putative 5-HT receptors. TM domains I-VII were were extracted from the alignment for bootstrapping (bootstrap value 1000). Outlined receptors are significantly diverged from vertebrate and ecdysozoan serotonin receptors. DtSER-1 (red) was amplified using a degenerate PCR strategy and was chosen to undergo RNAi-based deorphanization.