Table 1. Genome-wide LOD scores exceeding 2.0 in two-point MMLS linkage analysis for Reading Disability (RD) in original dataset; LOD scores for broader phenotypes (RD or Speech Sound Disorder (SSD) and RD or CentroTemporal Spikes (CTS)) at these loci also listed.
Chromosome | Marker (Flanking) | Max LOD RD | Max LOD RD or SSD | Max LOD RD or CTS |
1q42-43 | D1S1540 (D1S2709,D1S2850) | 2.87 (1.90, −5.06) | 1.46 (1.55 −1.62) | 1.55 (0.76, −1.56) |
2q14.2 | D2S2254 (D2S363,D2S347) | 2.10 (−0.98, −1.83) | 1.24 (0.29, 0.31) | 0.45 (0.74, 0.01) |
2q14.2 | D2S2116 (D2S286, D2S1777) | 2.23 (0.12, 1.19) | 2.20 (0.60, 1.93) | 1.62 (0.77, 0.78) |
6q25.2 | D6S441 (D6S1687,D6S419) | 2.11 (−0.42,1.06) | 1.37 (0.04, 0.95) | 0.48 (−0.29, 0.35) |
7q21.11 | D7S660 (D7S2443,D7S1528) | 3.05 (2.73, −0.95) | 1.75 (1.82, −1.14) | 1.13 (1.46, 1.68) |