Table 1.
Characteristics and outcomes of liver transplant patients stratified by post-operative nosocomial infection
| Characteristics (n=525) | No post-operative infection(n=451) | Post-operative infection (n=74) | P value |
|---|---|---|---|
| Age (years) | 52 [46–57] | 52 [47–57] | 0.66 |
| Gender (% male) | 66% (300/451) | 72% (53/74) | 0.80 |
| Race | 0.11 | ||
| Caucasian | 72% (326/451) | 64% (47/74) | |
| African American | 4% (17/451) | 5% (4/74) | |
| Hispanic | 20% (88/451) | 27% (20/74) | |
| Other | 4% (20/451) | 4% (3/74) | |
| Etiology | 0.24 | ||
| Hepatitis C Virus (HCV) | 28% (128/451) | 31% (23/74) | |
| HCV and alcohol | 21% (93/451) | 20% (15/74) | |
| Alcohol | 10% (44/451) | 8% (6/74) | |
| Hepatitis B virus | 4% (19/451) | 7% (5/74) | |
| Non alcoholic steatohepatitis | 2% (10/451) | 7% (5/74) | |
| Primary biliary sclerosis | 4% (19/451) | 0% (0/74) | |
| Primary sclerosing cholangitis | 10% (46/451) | 11% (8/74) | |
| Acute Liver Failure | 3% (13/451) | 3% (2/74) | |
| Cryptogenic Cirrhosis | 4% (16/451) | 4% (3/74) | |
| Other | 14% (63/451) | 9% (7/74) | |
| MELD | 25 [21–29] | 27 [22–31] | 0.17 |
| DRI score (n=453) | 1.47 [1.34–1.61] | 1.49 [1.36–1.65] | 0.42 |
| Albumin g/dl (n=457) | 3.1 [2.6–3.5] | 3.2 [2.6–3.6] | 0.53 |
| Operation time (min) | 305 [263–358] | 342 [283–428] | < 0.01 |
| Re-transplant | 2.2% (10/451) | 1.4% (1/74) | 0.61 |
| Re-operation (y/n) | 11% (50/451) | 31% (23/74) | < 0.01 |
| Kidney dysfunction-pre or post-op dialysis (y/n) | 8% (38/451) | 23% (17/74) | < 0.01 |
| Pre-op dialysis (y/n) | 8% (34/451) | 14% (10/74) | 0.10 |
| Post-op dialysis (y/n) | 7% (33/451) | 22% (16/74) | < 0.01 |
| Diabetes (y/n) | 17% (75/451) | 14% (10/74) | 0.50 |
| Pre-transplant location | 0.42 | ||
| ICU | 11% (49/451) | 18% (13/74) | |
| Hospital floor | 44% (200/451) | 42% (31/74) | |
| Home | 45% (202/451) | 41% (30/74) | |
| Outcome measures | |||
| CXR findings | |||
| Circulatory Overload | 27% (123/451) | 47% (35/74) | < 0.01 |
| Pleural effusion | 20% (91/451) | 42% (31/74) | < 0.01 |
| Atelectasis | 52% (236/451) | 69% (51/74) | < 0.01 |
| TRALI | 1% (5/451) | 3% (2/74) | 0.31 |
| Mortality | 2% (9/461) | 11% (8/74) | < 0.01 |
| ICU length of stay (days) | 0 [0–2] | 2 [1–5] | < 0.01 |
| Postoperative length of stay (days) | 9 [7–13] | 18 [14–30] | < 0.01 |