Table I.
Demographic characteristics in relation to rhabdoid tumors
| Characteristic | Controls (n=208,178) n (%) |
All cases (n=105) n (%) |
p- value a |
Rhabdoid sarcoma b (n=61) n (%) |
p- value |
AT/RT (n=44) n (%) |
p- value |
|---|---|---|---|---|---|---|---|
| Tumor stage | --- | --- | --- | ||||
| Localized | --- | 38 (36.9) | 16 (27.1) | 22 (50.0) | |||
| Regional | --- | 25 (24.3) | 15 (25.4) | 10 (22.7) | |||
| Distant | --- | 40 (38.8) | 28 (47.5) | 12 (27.3) | |||
| Sex | 0.4 | 0.6 | 0.4 | ||||
| Male | 106196 (51.0) | 58 (55.2) | 33 (54.1) | 25 (56.8) | |||
| Female | 101982 (49.0) | 47 (44.8) | 28 (45.9) | 19 (43.2) | |||
| Maternal age at birth | 0.6 | 0.2 | 0.06 | ||||
| <20 | 22670 (10.9) | 9 (8.6) | 7 (11.5) | 2 (4.5) | |||
| 20-29 | 108838 (52.3) | 51 (48.6) | 34 (55.7) | 17 (38.6) | |||
| 30-34 | 48180 (23.1) | 29 (27.6) | 17 (27.9) | 12 (27.3) | |||
| 35+ | 28452 (13.7) | 16 (15.2) | 3 (4.9) | 13 (29.5) | |||
| Mother’s race/ethnicity | 0.7 | 0.5 | 0.05 | ||||
| White non-Hispanic | 75677 (36.4) | 42 (40.0) | 22 (36.1) | 20 (45.5) | |||
| Hispanic of any race | 93563 (44.9) | 45 (42.9) | 31 (50.8) | 14 (31.8) | |||
| Other/not specified | 38938 (18.7) | 18 (17.1) | 8 (13.1) | 10 (22.7) | |||
| Maternal birthplace | 0.8 | 0.5 | 0.2 | ||||
| Born in US | 117430 (56.5) | 63 (60.0) | 35 (57.4) | 28 (63.6) | |||
| Mexico | 53011 (25.5) | 25 (23.8) | 18 (29.5) | 7 (15.9) | |||
| Other Foreign | 37495 (18.0) | 17 (16.2) | 8 (13.1) | 9 (20.5) | |||
| Father’s age | 0.9 | 0.6 | 0.6 | ||||
| <20 | 8058 (4.1) | 4 (4.0) | 3 (5.2) | 1 (2.3) | |||
| 20-29 | 87273 (44.8) | 44 (43.6) | 29 (50.0) | 15 (34.9) | |||
| 30-34 | 50099 (25.7) | 27 (26.7) | 16 (27.6) | 11 (25.6) | |||
| 35+ | 49185 (25.3) | 26 (25.7) | 10 (17.2) | 16 (37.2) | |||
| Father’s race | 0.04 | 0.06 | 0.004 | ||||
| White non-Hispanic | 72066 (34.6) | 47 (44.8) | 24 (39.3) | 23 (52.3) | |||
| Hispanic of any race | 89530 (43.0) | 43 (41.0) | 31 (50.8) | 12 (27.3) | |||
| Other/not specified | 46582 (22.4) | 15 (14.3) | 6 (9.8) | 9 (20.5) | |||
| Maternal education (years) c | 0.05 | 0.9 | 0.04 | ||||
| 8 or fewer | 24485 (13.6) | 7 (6.9) | 6 (10.5) | 1 (2.3) | |||
| 9-<12 | 33121 (18.4) | 16 (15.8) | 10 (17.5) | 6 (13.6) | |||
| 12 | 52427 (29.1) | 25 (24.8) | 16 (28.1) | 9 (20.5) | |||
| 13-15 | 35590 (19.8) | 25 (24.8) | 11 (19.3) | 14 (31.8) | |||
| 16+ | 34514 (19.2) | 28 (27.7) | 14 (24.6) | 14 (31.8) | |||
| Paternal education (years) c | 0.3 | 0.9 | 0.1 | ||||
| 8 or fewer | 24685 (14.6) | 8 (8.2) | 6 (11.1) | 2 (4.7) | |||
| 9-<12 | 25145 (14.9) | 14 (14.4) | 10 (18.5) | 4 (9.3) | |||
| 12 | 52104 (30.9) | 28 (28.9) | 17 (31.5) | 11 (25.6) | |||
| 13-15 | 29800 (17.7) | 21 (21.6) | 10 (18.5) | 11 (25.6) | |||
| 16+ | 36966 (21.9) | 26 (26.8) | 11 (20.4) | 15 (34.9) | |||
| Source of payment for prenatal care c |
0.006 | 0.6 | 0.001 | ||||
| Private | 91651 (50.8) | 65 (64.4) | 31 (54.4) | 34 (77.3) | |||
| Medi-Cal/other governmental/self-pay | 88918 (49.2) | 36 (35.6) | 26 (45.6) | 10 (22.7) |
a
P-values, computed by chi-square, compare each group of cases to controls. All p-values are two sided.
b
Rhabdoid sarcomas include renal tumors and extra-renal non-CNS tumors.
c
Not reported in all years of the study.