Table 2.

mGFR, eGFR and Difference (Error) at Baseline and Change Over Time

	Pooled (N=3531)	MDRD (N=840)	AASK (N=1094)	CSG (N=360)	DCCT (N=1237)
No. of subject-time measurements	19735	8049	8649	998	2039
Max no. of measurements per person	15	15	15	6	3
mGFR
Baseline (Intercept)	73.1 (71.6, 74.5); <0.001	33.0 (32.2, 33.8); <0.001	46.7 (45.8, 47.5); <0.001	74.6 (71.3, 78.0); <0.001	123.9 (122.7, 125.1); <0.001
Change (Slope)	−2.25 (−2.43, −2.06); <0.001	−3.34 (−3.59, −3.09); <0.001	−1.89 (−2.10, −1.69); <0.001	−5.25 (−6.27, −4.24); <0.001	−0.94 (−1.40, −0.48); <0.001
% Change (Slope)	−7.1% (−7.6, −6.6); <0.001	−15.7% (−16.8, −14.5); <0.001	−8.1% (−8.8, −7.3); <0.001	−11.8% (−13.7, −10.0); <0.001	−0.8% (−1.2, −0.4); <0.001
eGFR
Baseline (Intercept)	72.7 (71.5, 74.0); <0.001	35.1 (34.2, 36.0); <0.001	50.8 (49.7, 51.8); <0.001	76.7 (73.8, 79.6); <0.001	117.3 (116.6, 118.0); <0.001
Change (Slope)	−2.22 (−2.37, −2.07); <0.001	−3.37 (−3.64, −3.09); <0.001	−2.19 (−2.40, −1.99); <0.001	−4.52 (−5.46, −3.57); <0.001	−1.06 (−1.31, −0.80); <0.001
% Change (Slope)	−7.1% (−7.6, −6.6); <0.001	−15.5% (−16.7, −14.3); <0.001	−8.4% (−9.2, −7.6); <0.001	−0.10%(−11.7, −8.2); <0.001	−1.0% (−1.2, −0.7); <0.001
Difference (Error)
Baseline (Intercept)	0.14 (−0.35, 0.63); 0.6	−2.10 (−2.47, −1.73); <0.001	−4.04 (−4.56, −3.52); <0.001	−2.05 (−3.82, −0.28); 0.02	6.58 (5.39, 7.77); <0.001
Change (Slope)	−0.09 (−0.24, 0.05); 0.2	0.01 (−0.11, 0.14); 0.8	0.28 (0.15, 0.42); <0.001	−0.71 (−1.49, 0.08); 0.08	0.11 (−0.38, 0.59); 0.7
% Change (Slope)	−0.1% (−0.4, 0.1); 0.2	−0.3% (−0.7, 0.1); 0.1	0.2% (−0.1, 0.5); 0.3	−1.6% (−2.6, −0.5); 0.004	0.1% (−0.3, 0.6); 0.5

Except where indicated, values shown are given as estimate (95% CI); p. Unit for mGFR and eGFR and for the difference (error) is ml/min/1.73 m². Unit for change is ml/min/1.73 m² per year computed using non-log transformed values or % per year computed log transformed values. Intercepts for the model using log transformed values are not shown.

Max, maximum; MDRD - Modification of Diet in Renal Disease; AASK - African American Study of Kidney Disease and Hypertension; CSG Collaborative Study Group; DCCT - Diabetes Control and Complications Trial; eGFR, estimated glomerular filtration rate; mGFR, measured glomerular filtration rate