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PD genes are implicated in various aspects of mitochondrial biology. Products of autosomal recessive PD genes (shown in green) or autosomal dominant PD genes (shown in red) directly or indirectly affect a wide spectrum of mitochondrial processes, including their life cycle, bioenergetic capacity, quality control, dynamic changes of morphology and connectivity (fusion, fission), subcellular distribution (transport), and the regulation of cell death pathways.
