Table 9.

Completion of convergence and covariance steps for the final stepwise model and the single-objective, hybrid genetic algorithm (SOHGA) candidate model with lowest fitness function value

	Convergence		Covariance step (condition number)
	Final manual stepwise model	Best SOHGA candidate	Final stepwise model	Best SOHGA candidate
Citalopram, IV	Successful	Successful	Unsuccessful (N/A)	Successful (2,830)
DMAG, IV	Successful	Successful	Successful (20)	Successful (25)
Escitalopram [21]	Successful	Successful	Successful (39)	Successful (9)
Olanzapine, oral [14]	Required fixing K a early in model building process	Successful	Successful (12)	Successful (50)
Perphenazine, oral [15]	Required fixing K a early in model building process	Successful	Unsuccessful (N/A)	Successful (212)
Risperidone, oral [16]	Required fixing K a early in model building process	Successful	Successful (61)	Successful (1.17x106)
Ziprasidone, oral [17]	Required fixing K a early in model building process	Successful	Successful (3)	Successful (5)