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. 2012 Jul 19;3:119. doi: 10.3389/fphar.2012.00119

Figure 2.

Figure 2

Basal HO-1 protects against oxidation and inflammation. HO-1+/− and HO+/+ (WT) mice were subjected to partial liver warm ischemia for 90 min followed by 6 h of reperfusion. Two groups of mice were treated with CoPP. (A) Basal HO-1 mRNA levels, (B) Post-ischemia reperfusion (IR) HO-1 mRNA levels, (C) Basal HO-1 levels correlated negatively with post-IR serum GPT levels (R2 = 0.69, p < 0.0001) (D) HO-1 fold induction had a positive correlation with sGPT levels instead (R2 = 0.75, p = 0.0001). Taken from Tsuchihashi et al. (2006). Copyright 2006. The American Association of Immunologists, Inc.