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. Author manuscript; available in PMC: 2012 Jul 19.
Published in final edited form as: J Med Chem. 2009 May 28;52(10):3328–3341. doi: 10.1021/jm900253g

Figure 2.

Figure 2

Inhibition of human P-gp VER-stimulated ATPase activity. Histidine-tagged P-glycoprotein was expressed in BHK cells, isolated by nickel-chelate chromatography and mixed with lipid. P-glycoprotein ATPase activity was then measured in the presence of 0.4 mM VER with various concentrations of rhodamine derivatives 30-S, 30-Se, 30-Te, or 31-S. Data represent the average for triplicate measurements and error bars represent the standard deviation.