Figure 5.

Subicular encoding of object novelty. (A) Top, spectrogram showing spectral density for a single representative DS electrode during 2-s episodes of novel and familiar object exploration. The color scale (middle panel) varies from red (high power) to blue (low power), within 0–30 Hz frequency range. Bottom, unfiltered neural activity during the 2-s episodes. (B) Representative PSD plots taken only during periods of object exploration. The shaded areas under the curves represent the respective theta bands. On choice trials, DS-theta power increases specifically when mice explore the novel object (graph with theta band indicated in blue). (C) Left, graph displaying individual theta power ratios in the DS during sample (S1, n = 19, S2, n = 19) and choice (C1, n = 16, C2, n = 14) trials across all mice. Right, on average, the theta power ratio (mean ± SEM) is elevated on choice trials. (D) Graph showing that, in CA1, there is no difference in theta power ratios (mean ± SEM) between sample and choice trials. ^**p < 0.001 (t-test).