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. 2012 Jul 19;3:261. doi: 10.3389/fmicb.2012.00261

Table 3.

Chemosensitization of AMB by cinnamaldehyde*.

Strains Compounds MIC alone MIC combined FICI MFC alone MFC combined FFCI
C. albicans Cinn 0.8 0.8 2.0 1.6 0.8 0.8
ATCC 90028 AMB 2 2 4 1
C. albicans Cinn 0.8 0.8 2.0 1.6 0.8 1.0
CAN276 AMB 2 2 2 1
C. krusei Cinn 0.8 0.8 2.0 1.6 0.8 1.0
ATCC 6258 AMB 4 4 4 (99.8% killing) 2
C. krusei Cinn 0.8 0.8 2.0 0.8 0.8 2.0
CAN75 AMB 4 4 4 4
C. tropicalis Cinn 1.6 1.6 2.0 1.6 1.6 2.0
CAN286 AMB 2 2 4 4
C. neoformans Cinn 0.8 0.8 2.0 0.8 0.4 1.0
CN24 AMB 4 4 4 2 (99.8% killing)
t-Test Cinn P-values: not determined (neutral interaction) P < 0.1
AMB P < 0.1

MFCs are concentrations where ≥99.9% fungal death was achieved, except where noted in the table.

*Cinn, cinnamaldehyde (mM); AMB, amphotericin B (μg mL−1); MIC, minimum inhibitory concentration; MFC, minimum fungicidal concentration; FICI, fractional inhibitory concentration indices; FFCI, fractional fungicidal concentration indices.