Table 1.
Variable | C (7) | F (7) | FT (7) |
morphometric | |||
LV mass (g) | 0.73±0.03 | 1.3±0.01* | 1.2±0.01* |
RWT | 0.33±0.007 | 0.38±0.005* | 0.35±0.004 |
systolic function | |||
LVFS (%) | 40±1.5 | 36±1 | 40±1.6 |
LVEF (%) | 77±1.6 | 72±1.1 | 76±1.5 |
VCF (circ/sec) | 0.0053±0.0003 | 0.0046±0.0001 | 0.0052±0.0002 |
diastolic function | |||
IVRT (ms) | 22±0.4 | 27±0.9# | 0.22±0.6 |
nIVRT (ms) | 1.6±0.03 | 2.05±0.07# | 1.73±0.03 |
E/A ratio (ms) | 1.72±0.08 | 2.24±0.12# | 1.72±0.15 |
global index | |||
MPI | 0.32±0.02 | 0.41±0.02# | 0.33±0.01 |
Values are the mean ± SEM. The morphometric evaluation consisted of the assessment of left ventricular mass (LV mass) and relative wall thickness (RWT). Systolic function was evaluated by the left ventricular fractional shortening (LVFS), left ventricular ejection fraction (LVEF), and velocity of circumferential fiber shortening (VCF). Diastolic function was evaluated by the absolute and normalized LV isovolumetric relaxation time (IVRT and nIVRT, respectively) and the ratio of the maximal early diastolic peak velocity (E) and late peak velocity (A) of mitral flow (E/A ratio). Cardiac global function was evaluated by the myocardial performance index (MPI). * p<0.05 vs. C and # p<0.05 vs. C and FT (one-way ANOVA).