Figure 5.

Detection of the slaved species for a NF-κB pathway model. The modulus of the log-ratio, |log(c_i(t)/c^*_i(t))|, between actual and imposed trajectories has been calculated as a function of time for each species of the model of NFκB canonical pathway (proposed in Lipniacki et al., 2004), model ℳ(14, 25, 28) from Radulescu et al. (2008). If the modulus is close to zero (ratio close to one fold from above, or from below) the species is slaved, otherwise the species is slow. Among the slaved species, some have low concentrations and satisfy quasi-steady-state conditions, whereas other have large concentrations and are involved in quasi-equilibrium reactions.