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. 2011 Nov 17;4:137–145. doi: 10.2147/PGPM.S25418

Figure 5.

Figure 5

Influence of SULT1A1 copy number on fulvestrant (5A) and β-naphthol (5B) sulfation. Enzymatic activity was determined either colorimetrically (for β-naphthol) or by LC-MS/MS. Copy number–phenotype relationships were assessed by analysis of variance with phenotype as the dependent variable.

Abbreviation: LC-MS/MS, liquid chromatography–mass spectrometry/tandem mass spectrometry.