Figure 1.

The assessment of plasma and cardiac tissue levels of prostanoids. (A) Plasma levels of prostanoids from mice subjected to 45 min of LAD ligation with or without subsequent reperfusion. Values are fold changes compared with sham-operated mice at the same time points. (B) Prostanoids levels from mouse cardiac tissues subjected to 45 min of ischaemia with LAD ligation. (C) Prostanoid levels from mouse cardiac tissue subjected to 45 min of global ischaemia with the Langendorff perfusion system. Values are fold changes compared with sham hearts, which were subjected to 45 min of continuous perfusion instead of ischaemia. Data are presented as the mean ± SD, n = 4 in each group, *P < 0.05 compared with sham.