Table 1.
Distribution of covariates in case and matched control study participants.
Covariate | Cases | Controls |
---|---|---|
n | 239 | 472 |
Dehydroepiandrosterone, nmol/L | 17.1 (4.3, 46.7) | 16.6 (6.1, 37.9) |
Dehydroepiandrosterone sulfate, nmol/L | 1183 (465, 2389) | 1095 (484, 2483) |
Age at blood draw, years | 62 (51, 68) | 62 (50, 68) |
Current smokers | 78 (32.6) | 158 (33.5) |
Body mass index, kg/m2 | 25.9 (20.4, 35.3) | 24.4 (20.7, 31.3) |
Waist-to-hip ratio | 0.81 (0.72, 0.89) | 0.78 (0.71, 0.87) |
Average physical activity, MET-hours per week | 8.7 (1.2, 37.2) | 9.9 (1.0, 37.7) |
Alcohol consumption, g/day | 1.4 (0, 16.9) | 3.1 (0, 19.9) |
Parental history of myocardial infarction | 86 (36.0) | 102 (21.6) |
History of hypertension | 131 (54.8) | 126 (26.7) |
History of diabetes | 44 (18.4) | 29 (6.1) |
History of hypercholesterolemia | 25 (10.5) | 47 (10.0) |
Use of aspirin in 1988 | ||
None | 80 (33.5) | 149 (31.6) |
1–14 days per month | 88 (36.8) | 218 (46.2) |
>14 days per month | 63 (26.4) | 93 (19.7) |
Postmenopausala | 204 (85.4) | 396 (83.9) |
Use of female hormones in the 3 months before blood collection | 73 (30.5) | 171 (36.2) |
Plasma total cholesterol, mmol/L | 6.09 (4.74, 7.51) | 5.78 (4.64, 7.12) |
Plasma HDL cholesterol, mmol/L | 1.29 (0.90, 1.83) | 1.51 (1.05, 2.16) |
Ratio of plasma total to HDL cholesterol | 4.51 (3.13, 7.04) | 3.83 (2.55, 5.74) |
Plasma CRP, mg/L | 3.1 (0.7, 13.7) | 2.2 (0.5, 9.2) |
Data are median (10th, 90th percentile) or n (%). Median age (range; 10th, 90th percentiles) of diagnosis of myocardial infarction was 65.8 (44.9–76.2; 54.2, 73.6) years. Median time from blood sample to diagnosis of myocardial infarction was 4.6 (0.08–8.7; 1.25, 7.6) years. Information was available for the covariates in >95% of study participants, with the exception of waist-to-hip ratio (165 cases and 334 controls). MET, metabolic equivalent.
There were 23/204/12 cases and 57/396/19 controls of pre-/post-/uncertain menopausal status, respectively.