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. 2012 Jul 19;7(7):e41293. doi: 10.1371/journal.pone.0041293

Figure 2. The mRNA and protein expression of PLK4 in HCC by qRT-PCR and western blot. A.

Figure 2

Down-regulated expression of PLK4 mRNA was detected by qRT-PCR in 13 out of 20 HCC cases. The relative PLK4 mRNA expression was indicated by histogram (T, tumor tissue; N, the corresponding adjacent non-tumor liver tissues). B. The PLK4 mRNA levels was significantly decreased in HCC as determined by the Wilcoxon matched paired test. C. Decreased expression of PLK4 protein was shown by western blot in 15 out of 20 HCC tumor tissues. The relative PLK4 protein expression was shown. GAPDH was used as loading control. D. Intensity of PLK4 normalized to GAPDH was indicated Wilcoxon matched paired test.