Figure 5. AST-120 shows no effects on cardiac hypertrophy as well as pro-hypertrophic mRNA expression in the STNx model.

Compared to sham, STNx animals show a significant increase in cardiomyocyte cross-sectional area (A) and cardiac mRNA expression of ANP, β-MHC and α-SkM-Ac genes (B). There was no difference between untreated and AST-120-treated groups. **p<0.01, ***p<0.001 vs Sham.