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. 2012 Jul 19;7(7):e40587. doi: 10.1371/journal.pone.0040587

Table 3. Haplotypes of the BMP9 SNPs in cases and controls.

Haplotypes rs7923671T>C rs75024165C>T rs34379100A>C rs9421799C>A Frequency χ2(df = 1) P(χ2) P(MonteCarlo) OR 95%CI
OPLL Control
Haplotype 1 C T C A 0.37 0.19 70.22 <0.001 <0.01 2.37 1.93–2.90
Haplotype 2 T C A C 0.43 0.44 1.73 0.1882 1.00 0.89 0.74–1.06
Haplotype 3 T C A A 0.07 0.11 12.13 0.0005 1.00 0.58 0.42–0.79
Haplotype 4 T T A A 0.04 0.04 <0.001 0.9988 1.00 1.00 0.64–1.56
Other haplotypes 0.09 0.22

Note: Haplotype 1 includes the risk alleles of rs75024165 *T and rs34379100 *C (P<0.01).

*

p-value of haplotype by χ2 and Monte Carlo (Number of permutation = 100).