Figure 1.

Schematic floor plans—facility 1, plan 1. Three types of schematic floor plans that outline the layout of the rooms and floors, the hygiene zones, and traffic flow were generated from the information collected at the visited facilities. (A) Zoning scheme. The zoning scheme shows the various types of rooms, which are represented by icons. In addition, color coding indicates areas outside and within the barrier as well as the various functional units. (B) Flow and hygiene levels scheme. The flow and hygiene levels scheme shows the flow of personnel (caretaker, scientists), mice, and material (clean and soiled) and the various hygiene levels. (C) Functional unit scheme. Details of the functional use of the various units and access of the facility staff and scientists are presented. (D) Description of the icons and colors used in the various floor plans.