Fig. 9. Gene expression analyses of the endolymphatic duct phenotype in dr^J/dr^J and Gbx2-/-mutants.

(A,B) Adjacent sections of dr^J/+ inner ears probed for Gbx2 (A) and Wnt2b (B) transcripts. Gbx2 and Wnt2b are co-expressed in the base of the endolymphatic duct region (arrow). (C,D) Adjacent sections of dr^J/dr^J inner ears from a comparable region as (A,B) and probed for Gbx2 (C) and Wnt2b (D) transcripts. Gbx2 expression is present in dr^J/dr^J mutants but not Wnt2b. (E,F) In Gbx2 null embryos Lmx1a is present in the medial region (F), similar to the Gbx2 +/- embryos (E). Orientation and scale bar apply to all.