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. 2012 Jul;64(3):505–519. doi: 10.1124/pr.111.005363

Fig 2.

Fig 2.

Shape effects. A particle's shape can influence the rate of cellular uptake and body distribution. Particles can be designed to have increased distribution (spherical or disk-like), adherence to junction sites (rod-like), improved uptake by cells (softness), or improved penetration into various gaps (deformable particles).