Table II.
Diagnostic performance of CTCA in detecting significant stenosis
| Parameter | LM (n=24) | LAD (n=21) | LCx (n=17) | All segments (n=62) | All patients (n=24) |
|---|---|---|---|---|---|
| Sensitivity (95% CI) | 100% (29.2–100) | 100% (15.8–100) | 75% (19.4–99.4) | 89% (51.8–99.7) | 86% (42.1–99.6) |
| Specificity (95% CI) | 74% (52.8–91.8) | 68% (43.5–87.4) | 54% (25.1–80.8) | 68% (53.7–80.1) | 41% (18.4–67.1) |
| Positive predictive value (95% CI) | 38% (8.5–75.5) | 25% (3.2–65.1) | 33% (7.5–70.1) | 32% (14.9–53.5) | 38% (15.2–64.6) |
| Negative predictive value (95% CI) | 100% (79.4–100) | 100% (75.3–100) | 88% (47.4–99.7) | 97% (85.8–99.9) | 88% (47.4–99.7) |
| Accuracy (95% CI) | 79% (62.7–95.3) | 71% (50.5–91.5) | 59% (35.6–82.4) | 71% (59.7–82.3) | 54% (34.1–73.9) |
| Likelihood ratio | 4.2 | 3.2 | 1.6 | 2.8 | 1.5 |
| Cut-off value [mm2] | <6.19 | <4.78 | <4.97 | <5.29 | |
| SE 46% | SE 67% | SE 75% | SE 64% | ||
| SP 88% | SP 90% | SP 65% | SP 77% | ||
| Area under curve | 0.6788 | 0.8204 | 0.7243 | 0.7293 |
SE – sensitivity, SP – specificity