Table II.
Characteristics of patients with acute coronary syndrome stratified according to TIMI score
| Parameter | TIMI 1–2 (N=22) | TIMI 3–4 (N=91) | TIMI 5–7 (N=37) |
|---|---|---|---|
| Age [years] | 56±12 | 65±10# | 71±14# |
| BMI [kg/m2] | 28.7±4.0 | 29.8±4.7 | 29.1±6.0 |
| Diabetes mellitus [%] | 0 | 52.7 | 54.1 |
| Arterial hypertension [%] | 40.9 | 78.0** | 75.7** |
| Systolic blood pressure [mm Hg] | 152±31 | 151±24 | 148±27 |
| Diastolic blood pressure [mm Hg] | 90±14 | 90±14 | 90±15 |
| Coronary artery disease (CAD) [%] | 18.2 | 64.8# | 81.1# |
| Left ventricular insufficiency [%] | 0 | 3.3 | 8.1 |
| Ejection fraction [%] | 57.3±7.5 | 52.0±6.1** | 47.1±9.4# |
| Left ventricular mass [g] | 275±117 | 316±85** | 330±90** |
| Hemoglobin [g/dl] | 13.7±1.6 | 14.2±1.2 | 13.7±2.3 |
| LDL cholesterol [mmol/l] | 3.45±1.19 | 3.09±1.08 | 2.81±1.06 |
| HDL cholesterol [mmol/l] | 1.45±0.36 | 1.36±0.41 | 1.42±0.41 |
| Triglycerides [mmol/l] | 1.67±0.77 | 1.82±1.17 | 1.56±0.67 |
| Homocysteine [µmol/l] | 15.7±7.1 | 16.7±6.6 | 16.6±4.8 |
| Vitamin B12 [pg/ml] | 266±126 | 319±148 | 364±318 |
| Folic acid [ng/ml] | 4.93±2.37 | 6.51±3.69 | 7.10±6.26 |
| eGFR [ml/min/1.73 m2] | 81±30 | 73±22 | 66±28* |
| Cystatin C [mg/l] | 1.19±0.31 | 1.49±0.52** | 1.70±0.57# |
| CRP [mg/l] | 1.7±2.5 | 1.3±3.3 | 2.4±4.3 |
| CK-MB [U/l] | 22±9 | 31±41 | 36±36* |
| Troponin C [ng/ml] | 1.97±4.12 | 2.55±7.63 | 2.66±3.92 |
| NT-proBNP [pg/ml] | 750±261 | 1240±2399* | 5490±6870# |
| Urotensin II [ng/ml] | 3.60±2.20 | 3.14±1.99 | 2.61±1.47* |
Statistical significance vs. TIMI 1-2
*
p < 0.05
**
p < 0.01
#
p < 0.001
BMI – body mass index, eGFR – estimated glomerular filtration rate