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. Author manuscript; available in PMC: 2012 Jul 20.
Published in final edited form as: J Thromb Haemost. 2009 Jan 28;7(5):825–832. doi: 10.1111/j.1538-7836.2009.03306.x

Figure 1. Thrombin generation in hemophilia A and hemophilia B.

Figure 1

Contact pathway inhibited whole blood coagulation is initiated to clot upon addition of 5 pM relipidated tissue factor in hemophilia A (n=6, ▲) and hemophilia B (n=4, ◇) individuals. Thrombin generation is determined as thrombin-antithrombin complex formation (TAT) and compared to a cumulative control of 35 healthy individuals (■)[12]. All data are shown as the mean±SEM. Clot times (CT) are indicated as an arrow below the x-axis.