TABLE 4.

ASSOCIATION BETWEEN PREVALENT ASTHMA AT CARDIA YEAR 10 EXAMINATION (PREDICTOR) AND RISK FOR LOW CATEGORY OF SERUM ADIPONECTIN CONCENTRATIONS AT YEAR 15 EXAMINATION (OUTCOME)

	All Women			Premenopausal Women			Men
	n with Low Adiponectin/N	OR (95% CI)	P Value	n with Low Adiponectin/N	OR (95% CI)	P Value	n with Low Adiponectin/N	OR (95% CI)	P Value
Unadjusted model
Both current and not current smokers	248/1,455	1.53 (0.96, 2.42)	0.07	203/1,257	1.39 (0.82, 2.36)	0.22	481/1,164	0.53 (0.29, 0.98)	0.04
Adjusted models
Both current and not current smokers	248/1,455	1.22 (0.71, 2.11)	0.48	203/1,257	1.13 (0.60, 2.12)	0.71	481/1,164	0.54 (0.28, 1.04)	0.07
Current smokers only	67/267	1.21 (0.46, 3.22)	0.70	56/219	1.60 (0.55, 4.60)	0.39	102/242	0.93 (0.27, 3.25)	0.91
Not current smokers only	181/1,188	1.17 (0.60, 2.26)	0.64	147/1,038	0.93 (0.42, 2.06)	0.86	379/922	0.46 (0.21, 1.01)	0.052

Definition of abbreviation: CARDIA = Coronary Artery Risk Development in Young Adults; CI = confidence interval; OR = odds ratio.

Prevalent asthma was measured at CARDIA Year 10 examination; all other data are measured at Year 15 examination, unless otherwise indicated.

The adjusted models included age, race, body mass index, current smoking, history of diabetes, logarithmically transformed insulin resistance, and logarithmically transformed physical activity score measured at CARDIA Year 15 examination and history of hay fever (at Year 0 examination). Low serum adiponectin concentration category was defined by the low category of serum adiponectin concentration (<7 mg/L) at Year 15.

Results were unchanged if covariates at CARDIA Year 15 examination were substituted with those at Year 10 examination instead.