Table 2.
Characteristics of Patients
| Sex, n | |
| Male | 16 |
| Female | 20 |
| Median age at time of SBRT, years (range) | 67.5 (52–92) |
| Median KPS at time of SBRT (range) | 80 (60–100) |
| Median follow-up, months (range) | 15 (4–45) |
| Median interval between treatments, months (range) | 22 (0–92) |
| Initial Stage, n (%) | |
| I–II | 16 (44%) |
| III | 17 (47%) |
| IV | 3 (8%) |
| Type of initial radiation, n (%) | |
| Definitive | 24 (67%) |
| Postoperative | 7 (19%) |
| Palliative | 5 (14%) |
| Method of initial radiation, n (%) | |
| Three-dimensional conformal | 25 (69%) |
| IMRT | 11 (31%) |
| Median dose of initial radiation, Gy (range) | 61.5 (30–79.2) |
| Surgical history, n (%) | |
| Wedge resection | 2 (6%) |
| Lobectomy | 7 (19%) |
| Chemotherapy with initial treatment, n (%) | |
| Neo-adjuvant | 11 (31%) |
| Concurrent | 14 (38%) |
| Adjuvant | 7 (19%) |
| Size of recurrence, long axis, cm (range) | 1.7 (0.6–3.8) |
| Histology of recurrence, n (%) | |
| Adenocarcinoma | 14 (39%) |
| Squamous carcinoma | 12 (33%) |
| NSCLC, NOS | 8 (22% |
| Other | 2 (6%) |
| Type of recurrence, n (%) | |
| Isolated in-field recurrence | 11 (31%) |
| Isolated out-of-field recurrence | 13 (36%) |
| Recurrence in setting of disseminated disease | 12 (33%) |
| SBRT dose and fractionation | |
| 50 Gy in 4 fractions | 26 (72%) |
| 40 Gy in 4 fractions | 6 (17%) |
| Other | 4 (11%) |
| Maximum point dose combined radiation treatments, Gy (range) | 81.5 (59.4–134.6) |
Abbreviations: IMRT = intensity-modulated radiation therapy; KPS = Karnofsky performance status; NSCLC = non–small cell lung cancer; SBRT = stereotactic body radiation therapy.