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. Author manuscript; available in PMC: 2012 Jul 20.
Published in final edited form as: Bioorg Med Chem. 2011 Mar 27;19(10):3242–3248. doi: 10.1016/j.bmc.2011.03.054

Table 1.

IC50 values of phenyl, carbaboranyl and adamantyl esters in comparison to indomethacin.

graphic file with name nihms-285679-t0007.jpg
R IC50 (μM)
COX-1 COX-2
H (1) 0.05* 0.75*
o-C2B10H11 (5o) 2.60 4.20
m-C2B10H11 (5m) >25 >25
C10H15 (9) >25 >25
C6H5 (10) >25* 0.40*
*

already reported12