Table II.

Summary of SIV Gag peptide specific CD8⁺ T cell responses (frequency of the responding cells) after i.v. SIVmac239 challenge

		Functional Profilea				Apoptotic Signalsa
Animal	Weeks PC	IL-2 (%)	TNF-α (%)	IFN-γ (%)	CD107ab (%)	Bcl-2 (%)	Caspase-3 (%)
34569 Pb	4	0.14	—c	0.23	0.13	1.1	−0.9d
	7	0.27	0.79	0.48	0.05	3.7	0.25
	12	—b	0.23	0.3	—c	2.5	3.1
32212 P	4	0.17	—b	0.08	0.4	4.1	−0.5d
	7	0.12	0.40	0.43	1.11	5.1	−1.54d
	12	0.4	0.37	0.3	1.87	3.8	1.5
32273 Ue	4	—c	—c	0.08	—c	0.4	6.9
	7	—c	—c	—c	1.02	2.0	2.0
	12	0.4	1.73	1.67	0.81	−1.4d	16.7
30706 Ue	4	ND	ND	ND	ND	ND	ND
	7	0.29	0.17	0.20	1.25	2.1	0.1
	12	—c	—c	0.06	—c	1.5	4.1

^aData show the maximum value at 0.1 or 1 µg/ml peptide.

^bProtected.

^cValues less than the cutoff (<0.05%).

^dNegative net change (value in the DMSO control was higher than in the peptide stimulated sample).

^eUnprotected.