Table 1. A. muciniphila as a marker for a healthy intestine.
Percentage Akkermansia-like bacteria compared with total bacteria (based on qPCR) | Ratio Akkermansia in patients compared with healthy controls | |
---|---|---|
Healthy control | 2.91±0.90 | 1.00 |
UC | 0.02 | 0.0069 |
CD | 0.20 | 0.0687 |
Percentage Akkermansia-like bacteria (based on FISH) | Ratio Akkermansia in patients compared with healthy controls | |
---|---|---|
Healthy control | 4.0 | 1.00 |
Appendicitis | 0.20 | 0.05 |
Abbreviations: CD, Crohn's disease; FISH, fluorescence in-situ hybridization; IBD, inflammatory bowel disease; qPCR, quantitative PCR; UC, ulcerative colitis.
Intestinal disorders like appendicitis or IBD lead to reduction of A. muciniphila as compared with healthy controls.
Bold entries are values of the patient samples to emphasize the difference from the control.