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. Author manuscript; available in PMC: 2013 Mar 21.
Published in final edited form as: Bioconjug Chem. 2012 Mar 8;23(3):604–609. doi: 10.1021/bc200648m

Figure 2. An optimized regimen of PIT resulted in complete pathologic response in mice with A431 xenograft tumors.

Figure 2

(a) Repeated Pan-IR700 mediated PIT lead to more effective tumor volume reduction (n = 10 mice in each treatment group; *** P < 0.001 vs. non treatment control mice). Note that data were analyzed and shown only when each group of tumors were not exceeded 500 mm3. (b) Repeated Pan-IR700 mediated PIT led to prolonged survival. (n = 10 mice in each treatment group; *** P < 0.001, ** P < 0.01 vs. non treatment control mice).