Skip to main content
. 2012 Jul 20;7(7):e41345. doi: 10.1371/journal.pone.0041345

Table 2. Functional classification of differentially expressed proteins.

match set function RO− vs. RA−RO+ vs. RA+ RA+ vs. RA− RO+ vs. RO−
up-regulated TBA1A, TBA4A, TBA8A, TLN1, VINC TBA4A, TPM1, TPM3, TPM4, ARPC2, ACTN1, FLNA, TLN1, VINC, VIME, PLSL TBB5. TBA4A, FLNA, VINC, COF1, ARP3
structural molecules
down-regulated TBB5, TPM4, PROF1 ACTN1, TPM1, TPM2,VIME TPM1, FLNA
up-regulated ALDOA, TPIS, KPYM, ENOA, TKT, ATPB, ATP5H ENOA ATPB, ATP5H
energy metabolism
down-regulated ALDOA, PKM2 KPYM, LDHB, TALDO, ATP5H
up-regulated SODM, G6PD GSTO1, PRDX2
redox status
down-regulated THIO SODM, SH3L3
up-regulated ANXA5, LIMS1 GDIR1, ITA2B, 1433Z GDIR2
signaling
down-regulated TSP1, LIMS1 GRB2
up-regulated GRP78, HSP7C, PDIA3 HS90A, CH60, GRP78, HSP7C HS90A, GRP78, HSP7C, GRP75, PDIA3
cell stress, protein folding

RA− and RO− indicate the profiling results for the respective untreated T cell subsets, RA+ and RO+ for that of H2O2-treated T cell subpopulation as outlined in the Material and methods section. Proteins are listed by their protein entry names.