Table 2. Functional classification of differentially expressed proteins.
match set function | RO− vs. RA−RO+ vs. RA+ | RA+ vs. RA− | RO+ vs. RO− |
up-regulated | TBA1A, TBA4A, TBA8A, TLN1, VINC | TBA4A, TPM1, TPM3, TPM4, ARPC2, ACTN1, FLNA, TLN1, VINC, VIME, PLSL | TBB5. TBA4A, FLNA, VINC, COF1, ARP3 |
structural molecules | |||
down-regulated | TBB5, TPM4, PROF1 | ACTN1, TPM1, TPM2,VIME | TPM1, FLNA |
up-regulated | ALDOA, TPIS, KPYM, ENOA, TKT, ATPB, ATP5H | ENOA | ATPB, ATP5H |
energy metabolism | |||
down-regulated | ALDOA, PKM2 | KPYM, LDHB, TALDO, ATP5H | |
up-regulated | SODM, G6PD | GSTO1, PRDX2 | |
redox status | |||
down-regulated | THIO | SODM, SH3L3 | |
up-regulated | ANXA5, LIMS1 | GDIR1, ITA2B, 1433Z | GDIR2 |
signaling | |||
down-regulated | TSP1, LIMS1 | GRB2 | |
up-regulated | GRP78, HSP7C, PDIA3 | HS90A, CH60, GRP78, HSP7C | HS90A, GRP78, HSP7C, GRP75, PDIA3 |
cell stress, protein folding |
RA− and RO− indicate the profiling results for the respective untreated T cell subsets, RA+ and RO+ for that of H2O2-treated T cell subpopulation as outlined in the Material and methods section. Proteins are listed by their protein entry names.