Table 4. mRNA expression levels of previously identified vaccine candidates [8].
| Category | Gene ID | Annotation | C. immitis expression* | C. posadasii expression* | Differential regulation** |
| Proline-rich proteins | CIMG_09696 | Prp1 | 35,414 | 55,176 | No |
| CIMG_09560 | Prp2 | 149 | 129 | No | |
| CIMG_02492 | Prp3 | 124 | 666 | No | |
| CIMG_07303 | Prp4 | 62 | 46 | Up H (3.9-fold) | |
| CIMG_05560 | Prp5 | 170 | 108 | No | |
| CIMG_07843 | Prp6 | 384 | 485 | No | |
| CIMG_09029 | Prp7 | 39 | 61 | No | |
| CIMG_02073 | Prp8 | 241 | 223 | Up S (2.2-fold) | |
| Low polymorph., High T-cell epitope | CIMG_00642 | Conserved hypothetical protein (putative COPI-associated protein) | 941 | 651 | No |
| CIMG_02599 | Conserved hypothetical protein (DUF2015) | 2,822 | 3,078 | No | |
| CIMG_03437 | Conserved hypothetical protein | 883 | - | No | |
| CIMG_04746 | Conserved hypothetical protein | 902 | 664 | No | |
| CIMG_04894 | Conserved hypothetical protein | 814 | 1,168 | No | |
| CIMG_07187 | Iron/copper transporter Atx1 | 724 | 776 | No | |
| CIMG_07738 | Conserved hypothetical protein | 384 | 325 | Up H (15-fold) | |
| CIMG_08533 | Golgi membrane protein YIPF5 | 800 | 548 | No | |
| CIMG_09101 | Unfolded protein response protein Orm1 | 103 | 74 | No | |
| CIMG_10953 | Conserved hypothetical protein | 1,929 | 1,327 | No | |
| CIMG_11035 | Conserved hypothetical protein | 814 | 1,378 | No | |
| CIMG_12464 | Integral membrane protein | 746 | 306 | No |
*
Parasitic phase expression levels are normalized by library size and gene length.
**
Differential regulation: Up H: up-regulated in hyphae (saprobic phase), Up S: up-regulated in spherules (parasitic phase).