Table 2. Details on the brain regions in the DMN map (P<0.01, FDR corrected) from the healthy controls and MHE patients.

Anatomical region	Hemisphere	MNI coordinates (x, y, z)	Brodmann's area	Cluster size (Voxels)	t value
Healthy controls
PCC/PCUN	L/R	0, −51, 30	7, 23, 26, 30	2212	15.32
IPL	L	−68, −66, 30	39, 40	359	16.17
	R	57, −63, 27	39, 40	279	15.15
PHG	L	−27, −24, −15	35, 36	86	6.51
	R	30, −30, −15	35, 36	50	4.77
ITG	L	−57, −21, −18	20, 21,38	522	9.50
	R	54, 0, −33	20, 21,38	488	9.76
MPFC	L/R	3, 42, −18	8, 9, 10, 11, 32	3183	13.64
MHE patients
PCC/PCUN	L/R	6, −51, 33	7, 23, 26, 30	2389	16.09
IPL	L	−45, −72, 42	39, 40	304	15.11
	R	51, −66, 30	39, 40	318	13.94
PHG	L	−27, −33, −15	35, 36	60	5.97
	R	30, −27, −18	35, 36	55	6.67
ITG	L	−60, −9, −18	20, 21,38	424	8.91
	R	60, −6, −24	20, 21,38	356	9.15
MPFC	L/R	−6, 48, −9	8, 9, 10, 11, 32	3141	10.46

DMN = default mode network; FDR = false discovery rate; MHE = minimal hepatic encephalopathy; PCC/PCUN = posterior cingulate cortex/precuneus; MPFC = medial prefrontal cortex; PHG = parahippocampal gyrus; MNI = Montreal Neurological.