Table 2.
CD30 expression in various T-cell subsets in patients after allogenic HCT
T-cell subset | GVHD | NONE | P |
---|---|---|---|
All CD4 | 3.1 (0.1-21.3) | 1.4 (0.4-10.3) | .100 |
Naïve CD4 | 0.2 (0.0-3.4) | 0.2 (0.0-16.7) | .348 |
Central memory CD4 | 5.0 (0.1-41.0) | 2.4 (0.9-23.3) | .054 |
Effector memory CD4 | 2.6 (0.3-10.9) | 1.7 (0.6-5.8) | .482 |
Regulatory T cells | 10.1 (2.4-27.6) | 6.2 (0.0-20.8) | .155 |
All CD8 | 2.3 (0.3-18.2) | 0.6 (0.2-3.2) | < .001 |
Naïve CD8 | 0.5 (0.0-16.2) | 0.3 (0.0-2.9) | .500 |
Central memory CD8 | 12.4 (0.8-33.4) | 2.1 (0.7-17.5) | < .001 |
Effector memory CD8 | 2.4 (0.7-10.8) | 0.8 (0.3-2.9) | < .001 |
Subsets were defined phenotypically as discussed in “Flow Cytometry.” Values for GVHD and NONE groups are given as the percentage of cells in each subset expressing CD30. Range of values is given in parentheses.
HCT indicates hematopoietic cell transplantation.