Table 1. Summary of the different parameters measured at the indicated time point in the trial.
Plasma | Baseline | BF 400 mg | BF 800 mg |
Total cholesterol (mmol/L) | 5.57±1.42 | 4.80±0.88** | 4.85±0.84* |
LDL(mmol/L) | 3.67±1.17 | 2.93±0.80** | 2.90±0.73* |
HDL(mmol/L) | 1.39±0.25 | 1.57±0.25*** | 1.64±0.26*** |
TG(mmol/L) | 1.34±0.79 | 0.70±0.31** | 0.71±0.22* |
C22∶0(µmol/L) | 43.32±9.25 | 45.37±8.12 | 55.02±9.74** |
C24∶0(µmol/L) | 62.56±11.68 | 64.08±11.78 | 82.62±12.50*** |
C26∶0(µmol/L) | 3.26±0.96 | 2.56±0.50** | 2.99±0.49 |
C26∶0/C22∶0 ratio | 0.075±0.015 | 0.058±0.012 | 0.056±0.012** |
Bezafibrate(µmol/L) | n.d. | n.d. | 10.1±6.7 |
Lymphocytes | |||
C22∶0(nmol/mg) | 5.89±1.03 | 5.85±1.65 | 5.10±1.47 |
C24∶0(nmol/mg) | 6.03±0.78 | 6.45±1.85 | 6.42±1.44 |
C26∶0(nmol/mg) | 0.35±0.040 | 0.37±0.084 | 0.40±0.11 |
C26∶0/C22∶0 ratio | 0.06±0.01 | 0.06±0.01 | 0.08±0.03 |
bloodspots | |||
C26∶0 lysoPC | 2.84±1.40 | 2.50±0.89 | 2.63±1.18 |
Weight (kg) | 86.7±9.3 | n.d. | 87.9±10.5 |
Values are mean ± the standard deviation. Statistically significant differences from the baseline value are indicated.
p<0.05,
p<0.01,
p<0.001. n.d. = not determined.