Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Jul 20;7(7):e39407. doi: 10.1371/journal.pone.0039407

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Pasotti et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

A) Schematic functional representation of the tested framework. B) Different input devices are assembled upstream of a tetR-based logic inverter. They provide transcriptional signals that drive the inverter. C) INPUT1: a set of four constitutive promoters of different strengths. D) INPUT2: promoter, which is repressed by the endogenously-overexpressed lacI and can be induced by IPTG. E) INPUT3: luxR-based HSL-inducible device. can be induced by LuxR-HSL complex. The luxR gene is produced by the weak basic activity of repressed in absence of IPTG. IPTG = isopropyl -D-1-thiogalactopyranoside; HSL = N-3-oxohexanoyl-L-homoserine lactone.

Inline graphic — A) Schematic functional representation of the tested framework. B) Different input devices are assembled upstream of a tetR-based logic inverter. They provide transcriptional signals that drive the inverter. C) INPUT1: a set of four constitutive promoters of different strengths. D) INPUT2: promoter, which is repressed by the endogenously-overexpressed lacI and can be induced by IPTG. E) INPUT3: luxR-based HSL-inducible device. can be induced by LuxR-HSL complex. The luxR gene is produced by the weak basic activity of repressed in absence of IPTG. IPTG = isopropyl -D-1-thiogalactopyranoside; HSL = N-3-oxohexanoyl-L-homoserine lactone.