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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Mol Immunol. 2012 Jun 4;52(3-4):165–173. doi: 10.1016/j.molimm.2012.04.013

Figure 1. Location of rs3813946 within the proximal promoter region of the human CR2 gene.

Figure 1

The nucleotide sequence from the -133 upstream promoter region to the translation start site of the CR2 gene is shown. Previously identified functional elements, an AP2-like site and the Ebox1 and Ebox2 are shaded. Recently identified transcription factor binding sites for PAX5, C/EBP β and MAZ are shown as boxed regions. The transcription and translation start site is indicated with arrows. The putative TATA box binding site is in bold font. The single-nucleotide polymorphism studied herein (rs3813946) is indicated in the sequence at its nucleotide position (+21T/C).