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. 2012 May 18;29(7):643–650. doi: 10.1007/s10815-012-9780-4

Table 1.

In vivo and in vitro developmental potentials of oocytes collected from the mice at young and old age

Group In vivo development In vitro development
Individuals (n) Pregnancies (n, % ± SE) Total litter size (n) Average litter size (n ± SE)a Stillbirth plus fetal malformations (n, % ± SE)b Individuals (n) No. of oocytes 2-cell (% ± SE) Blastocyst (% ± SE)
Old 15 8 (46.7 ± 6.7)c 98 12.3 ± 0.5c 17 (17.2 ± 0.9)c 20 212 149 (69.9 ± 0.9)c 72 (33.9 ± 0.3)c
Young 15 15 (100 ± 0.0)d 205 13.7 ± 0.4c 6 (2.9 ± 0.8)d 9 249 202 (80.9 ± 1.2)d 126 (56.4 ± 1.9)d

aAverage litter size was compared only in the mice that had successfully given birth at both young and old age

bStillbirth and fetal malformation rate is the percentage of total litter size

c,dDifferent superscripts within same column indicate statistically significant difference (P < 0.05)