Table 1.
In vivo and in vitro developmental potentials of oocytes collected from the mice at young and old age
Group | In vivo development | In vitro development | |||||||
---|---|---|---|---|---|---|---|---|---|
Individuals (n) | Pregnancies (n, % ± SE) | Total litter size (n) | Average litter size (n ± SE)a | Stillbirth plus fetal malformations (n, % ± SE)b | Individuals (n) | No. of oocytes | 2-cell (% ± SE) | Blastocyst (% ± SE) | |
Old | 15 | 8 (46.7 ± 6.7)c | 98 | 12.3 ± 0.5c | 17 (17.2 ± 0.9)c | 20 | 212 | 149 (69.9 ± 0.9)c | 72 (33.9 ± 0.3)c |
Young | 15 | 15 (100 ± 0.0)d | 205 | 13.7 ± 0.4c | 6 (2.9 ± 0.8)d | 9 | 249 | 202 (80.9 ± 1.2)d | 126 (56.4 ± 1.9)d |
aAverage litter size was compared only in the mice that had successfully given birth at both young and old age
bStillbirth and fetal malformation rate is the percentage of total litter size
c,dDifferent superscripts within same column indicate statistically significant difference (P < 0.05)