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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Microvasc Res. 2012 Jun 5;84(2):155–160. doi: 10.1016/j.mvr.2012.05.009

Figure 2. Hydrogen peroxide increases the half-life of PLGF mRNA.

Figure 2

Human CASMC were treated with either actinomycin D (10 µg/mL) alone or with actinomycin D (10 µg/mL) plus a single dose of H2O2 (50 µM) and mRNA was collected at 0, 2, 4, 8 and 16 h later. PLGF mRNA transcript half-life was significantly (*p<0.01, n=3) increased at 2, 4, and 8 h post treatment with H2O2. There was no significant difference in PLGF mRNA levels at 0 and 16 h (n=3).