Fig. 2.

Count for K16 and leukocytes in early-stage psoriatic lesions. Biopsies were taken from non-lesional skin (d0 NL) and incipient psoriatic lesions at baseline and 1 and 2 weeks later (d0 L, d7 L, d14 L, respectively). Cryostat sections were stained for K16 expression and the presence of CD3⁺, CD4⁺, and CD8⁺ T cells, CD1a⁺ Langerhans cells and dendritic cells, CD11c⁺ dendritic cells, CD14⁺ macrophages and BDCA-2⁺ plasmacytoid dendritic cells. The two top rows are countings of the epidermis while the bottom two rows are dermal cell numbers. Closed symbols represent cell numbers of the three cases that showed a decline of epidermal thickness and K16 expression from d7 to d14, while the open symbols represent the three cases that showed increment of epidermal thickness and K16 expression from d0 to d14. Statistics of all these numbers are depicted in Table 1