Table 1.

Correlation of K16, epidermal thickness and leukocyte markers in early-stage psoriasis lesions

Cell markers	Anatomical sites	Correlations	∆(d7–d0)		∆(d14–d7)
			r	p	r	p
K16	Epidermis	vs. ∆ Epi thickness	0.943	0.005	0.943	0.005
CD3	Epidermis	vs. ∆ Epi thickness	0.371	0.468	0.771	0.072
		vs. ∆ K16 cells	0.2	0.704	0.829	0.042
	Dermis	vs. ∆ Epi thickness	0.429	0.397	0.886	0.019
		vs. ∆ K16 cells	0.657	0.156	0.943	0.005
CD4	Epidermis	vs. ∆ Epi thickness	0.257	0.623	0.371	0.468
		vs. ∆ K16 cells	0.371	0.468	0.257	0.623
	Dermis	vs. ∆ Epi thickness	0.314	0.544	0.886	0.019
		vs. ∆ K16 cells	0.486	0.329	0.943	0.005
CD8	Epidermis	vs. ∆ Epi thickness	0.6	0.208	0.829	0.042
		vs. ∆ K16 cells	0.657	0.156	0.771	0.072
	Dermis	vs. ∆ Epi thickness	0.657	0.156	0.943	0.005
		vs. ∆ K16 cells	0.429	0.397	1	<0.001
CD11c	Epidermis	vs. ∆ Epi thickness	0.2	0.704	0.6	0.208
		vs. ∆ K16 cells	0.371	0.468	0.714	0.111
		vs. ∆ CD3 cells	0.486	0.329	0.943	0.005
	Dermis	vs. ∆ Epi thickness	0.943	0.005	0.943	0.005
		vs. ∆ K16 cells	0.886	0.019	1	<0.001
		vs. ∆ CD3 cells	0.371	0.468	0.943	0.005
CD1a	Epidermis	vs. ∆ Epi thickness	0.086	0.872	−0.886	0.019
		vs. ∆ K16 cells	0.029	0.957	−0.771	0.072
	Dermis	vs. ∆ Epi thickness	0.657	0.156	0.429	0.397
		vs. ∆ K16 cells	0.486	0.329	0.6	0.208
CD14	Epidermis	vs. ∆ Epi thickness	−0.091	0.864	0.516	0.295
		vs. ∆ K16 cells	−0.03	0.95	0.698	0.123
	Dermis	vs. ∆ Epi thickness	0.429	0.397	0.771	0.072
		vs. ∆ K16 cells	0.657	0.156	0.829	0.042
BDCA-2	Dermis	vs. ∆ Epi thickness	0.771	0.072	0.6	0.208
		vs. ∆ K16 cells	0.543	0.266	0.657	0.156

Markers indicated in the first column are compared with changes (vs. ∆) in epidermal thickness (Epi thickness), K16⁺ keratinocyte (ΔK16 cells) or CD3⁺ T cell numbers (ΔCD3 cells) from d0 to d7 [Δ(d7–d0)] or d7 to d14 [Δ(d14–d7)]. All other combination of markers that are not indicated in this table did not reach significant correlation

Statistic significant correlations are depicted in bold. r = correlation factor, p = value of significance