Fig. 4.

Oct-1 inhibits (IL-6+IL-1β)-induced CRP promoter-driven Luc activity. Luc-157 WT and Luc-300 WT CRP promoter constructs were transfected into Hep3B cells along with increasing amounts of the expression vector encoding Oct-1. After 16 h, cells were treated with IL-6 and IL-1β for 24 h. CRP expression was measured as Luc activity. Percent inhibition of Luc activity is plotted on the y-axis. Average ± S.E.M. of three experiments are shown. For some data points, error bars are not visible because the S.E.M. was low.